Abstract
Conclusion:
Our data showed that there is no significant relationship between serum sex hormone levels and O-CAD.
Results:
Obstructive CAD (O-CAD) was detected in 75 (60 m, 15 f) patients. The mean age was 60.1 ± 14.2 in the O-CAD group and 59.2 ± 11.2 in the Non-O-CAD group. Serum/plasma HbA1c levels and having male gender were significantly higher in the O-CAD group. (p = .002, p = .008). Serum sex hormones were shown to have no significant differences between groups.
Method:
A hundred patients enrolled in the study. Patients were divided two groups based on the presence of lesions that causes luminal narrowing more than % 50 in at least one epicardial coronary artery.
Objectives:
The relationship between sex hormones such as estrogen, testosteron and coronary artery disease (CAD) has been found to be controversial in various studies. Moreover, recent studies revealed an association between CAD and dehydroepiandrosterone sulphate (DHEA-S) which is an endogenous steroid hormone and the precursor of sex hormones. We aimed to investigate the relationship between serum testosterone, estrogen, DHEA levels and CAD.
Keywords: Coronary artery disease, inflammation, sex hormones
