A Rarely Encountered Benign Proliferative Lesion of the Breast: Pseudoangiomatous Stromal Hyperplasia (PASH)
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Original Investigation
P: 90-92
April 2017

A Rarely Encountered Benign Proliferative Lesion of the Breast: Pseudoangiomatous Stromal Hyperplasia (PASH)

GMJ 2017;28(2):90-92
1. Gazi Üniversitesi Tıp Fakültesi, Genel Cerrahi Anadilim Dalı, Ankara, Türkiye
2. Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Ankara, Türkiye
3. Gazi Üniversitesi Tıp Fakültesi, Patoloji Anadilim Dalı, Ankara, Türkiye
No information available.
No information available
Received Date: 15.11.2016
Accepted Date: 08.01.2017
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ABSTRACT

Conclusion:

PASH, even though being benign and encountered rarely, must absolutely be taken into account in the differential diagnosis of patients with a breast mass detected radiologically or clinically. Histopathological diagnosis must be supported by immunohistochemical staining.

Results:

Four patients have been presented with complaints of enlarging breast mass while the other with haemorrhagic nipple discharge. Ages ranged from 25 to 50 with the meanage of 35. Pathologic diagnosis was made by the examination of core biopsy in 1 case, ultrasound-guided core biopsy in 2 cases, stereotactic-guided excisional biopsy in 1 case, and wide excisional biopsy in 1 case.

Materials and methods:

Five patients, attending to Gazi University Medical Faculty Hospital and diagnosed pathologically as PASH were examined retrospectively. The patients were re-evaluated by data concerning their age, complaints, family history, radiological findings and diagnostic methods.

Objective:

Pseudoangiomatous stromal hyperplasia (PASH), a benign proliferative lesion of breast stroma, is a mass lesion including anastomosing clefts reminiscent of blood vessels. It is still having an indefinite etiology and pathogenesis, and thought to represent a neoplastic process of myofibroblastical cell origin. The objective of this study is to evaluate the clinical and histopathological features and surgical indications of the patients diagnosed as PASH.