ABSTRACT

We report a case of lung cancer with multiple metastases to the brain. A 55-year-old man suffered onset severe cough and dyspnea. He had no history of any systemic disease. Standard blood work-up was normal. Computed tomographic and bronchoscopic biopsy identified an asymptomatic primary pulmonary large cell neuroendocrine carcinoma in the left upper lobe of the lungs and less differentiated squamous cell carcinoma right upper lobe of the lungs. He also received chemotherapy and radiation therapy to treat the primary lung cancer. Magnetic resonance imaging of the brain revealed multiple intracranial tumors, including3 cmmetastatic mass in left temporal lobe and3,5 cm metastatic mass in right frontal lobe. There were no metastatic findings in any other organs. First of all, the patient underwent a right frontotemporal approach with total microsurgical resection and after time underwent a left temporal approach with total microsurgical resection . He made good recovery and discharged.