ABSTRACT

Castleman’s disease (CD), or angiofollicular lymph node hyperplasia, is a rare, benign disease of unknown etiology giv-ing rise to lymph node hyperplasia. This disease creates both diagnostic and therapeutic dilemmas for most physicians. Tissue biopsy is necessary for a definitive diagnosis. CD of the submandibular gland occurs very rarely. Surgery is the treatment of choice for the solitary form in the neck region. We present a 42 year-old woman with CD of submandibular gland together with the review of the literature. (Gazi Med J 2011; 22: 97-9)