ABSTRACT
EDTA-dependent pseudothrombocytopenia (EDTA-PTCP) is a phenomenon caused by EDTA- dependent anti-platelet antibody. It is necessary for clinicians to consider the possible presence of PTCP in cases of patients having low platelet counts without any hemorrhagic tendency. We here present a EDTA-dependent pseudothromboctyopenia case which might be associated with rheumatoid arthritis and/or the medications such as sulfasalazine, leflunomide and methylprednisolone. As a conclusion pseudothrombocytopenia should be excluded in all thrombocytopenic patients without any hemorrhagic tendency by manual peripheric smear to avoid unnecessary diagnostic tests and wrong treatments.