ABSTRACT

We present a new case of Guillain-Barre syndrome following hepatitis B vaccine and review other cases in the literature. A 14-year-old male patient developed flaccid paralysis after immunization with recombinant hepatitis B vaccine 14 days before. Cerebrospinal fluid analysis revealed acellular fluid with a high protein level. The nerve conduction study was compatible with motor polyneuropathy. Other potential causes of Guillain-Barre syndrome were ruled out. Mechanisms of this very rare complication are proposed along with a literature review.