ABSTRACT

Extramedullary or extraosseous plasmacytoma (EMP) is a rare neoplasm characterized by monoclonal proliferation of plasma cells arising outside the bone marrow. It shows a predilection for the head and neck region, primarily in the upper respiratory tract. The commonest site of occurrence are nasal cavities and nasal septum followed by oropharynx. Eventhough EMP of the nasal cavity is rare but it should be considered in the differential diagnosis of nasal cavity mass. This tumour may invade into the adjacent tissues and acts as a locally aggressive neoplasms. Thus, crucial attention to the clinical, radiological, and histopathological findings should be taken into consideration for accurate diagnosis. Furthermore, appropriate management must be carried out to prevent further dissemination of the disease. We report a case of a 54-year-old male who presented with a progressive nasal blockade for one-year duration, in which the biopsy of the left nasal cavity mass revealed EMP. He underwent endoscopic debulking surgery and then was subjected for radiotherapy. The clinical and histopathologic findings of plasmacytoma are discussed further.