THE EFFECT OF THE USE OF AZELASTINE HCL AND TRIAM-CINOLONE ACETONIDE ON SYMPTOMS IN PATIENTS WITH SEASONAL ALLERGIC RHINITIS
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Original Investigation
P: 173-175
October 2009

THE EFFECT OF THE USE OF AZELASTINE HCL AND TRIAM-CINOLONE ACETONIDE ON SYMPTOMS IN PATIENTS WITH SEASONAL ALLERGIC RHINITIS

GMJ 2009;20(4):173-175
1. Numune Hastanesi, 3.KBB Kliniği, Ankara, Türkiye
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ABSTRACT

Conclusion:

The use of topical corticosteroids is more effective than that of topical antihistamines.

Results:

Azelastine topical spray was ineffective on the symptoms of pa-tients with seasonal allergic rhinitis. However, topical triamcinolone ace-tonide achieved greater relief of allergic rhinitis’ symptoms in the first and last 15 days.

Materials and Methods:

A total 20 adult patients 18-45 years old were enrolled in the study. Prick test results of all patients were highly positive. All patients took oral levocetirizine 2-HCl, with the first 10 patients taking topical azelastine HCl and the other 10 patients taking topical triamcinolo-ne acetonide. We determined total symptom scores of all patients through daily questionnaires. Analysis of patient based symptom scores and daily symptom scores for the first and last 15 days were evaluated

Purpose:

The use of antihistamine and topical nasal steroids represents the cornerstone of the pharmacologic treatment of allergic rhinitis. Anti-histamines can be used topically or orally. This study compared the effici-ency of intranasal azelastine HCl and intranasal triamcinolone acetonide on symptoms in patients with seasonal allergic rhinitis

Keywords:
Allergic Rhinitis, Triamcinolone Acetonide, Azalastine HCl