ABSTRACT

The use of topical corticosteroids is more effective than that of topical antihistamines.

Azelastine topical spray was ineffective on the symptoms of pa-tients with seasonal allergic rhinitis. However, topical triamcinolone ace-tonide achieved greater relief of allergic rhinitis’ symptoms in the first and last 15 days.

A total 20 adult patients 18-45 years old were enrolled in the study. Prick test results of all patients were highly positive. All patients took oral levocetirizine 2-HCl, with the first 10 patients taking topical azelastine HCl and the other 10 patients taking topical triamcinolo-ne acetonide. We determined total symptom scores of all patients through daily questionnaires. Analysis of patient based symptom scores and daily symptom scores for the first and last 15 days were evaluated

The use of antihistamine and topical nasal steroids represents the cornerstone of the pharmacologic treatment of allergic rhinitis. Anti-histamines can be used topically or orally. This study compared the effici-ency of intranasal azelastine HCl and intranasal triamcinolone acetonide on symptoms in patients with seasonal allergic rhinitis