ABSTRACT

Conclusion:

The consistency of the improvements in main outcome measures and their maintenance over time in our study suggest that pump therapy is safe and effective in diabetic Turkish children.

Results:

Although statistically insignificant, HbA1c tended to be lower com-pared to the pre-pump period. Body mass index Z scores remained similar (0.45±0.76 vs. 0.54±0.53 kg/m2, p>0.05). Insulin doses decreased (1.1±0.2 vs. 0.9±0.1 U/kg/day, p<0.01). Rates of certain episodes (event/patient-year) dec-reased: overall hyperglycemia; 244.0±84.5 vs. 90.6±38.9, Dawn phenomenon; 20.6±25.8 vs. 4.6±5.2, Somogyi phenomenon; 3.1±2.7 vs. 1.1±1.0, nocturnal hypoglycemia; 6.4±4.5 vs. 2.9±1.9, asymptomatic hypoglycemia; 21.3±13.4 vs. 8.8±6.7, symptomatic hypoglycemia; 3.7±2.2 vs. 1.6±1.3 (p values <0.05). Diabetic ketoacidosis rates were similar (0.24 vs. 0.30, p>0.05).

Materials and Methods:

Ten children (age; 14.7±2.6 years, pump therapy du-ration; 3-24 months) were prospectively studied. Main outcome measures were compared with those of the 12 months prior to pump therapy.

Purpose:

Although its use is increasing in children, there are no data about pump use in Turkish children with diabetes. The aim of this study was to inves-tigate the outcome measures of insulin pump use in diabetic Turkish children.