ABSTRACT

Vitamin D deficiency was found in 37.9% of the patients (53.2% in women and 15.1% in men). The frequency of vitamin D deficiency in obese female patients wearing covered dress was 71.9%. Female pa-tients who are vitamin D deficient had increased BMI, PTH and decre-ased apolipoprotein A and HDL cholesterol levels compared to vitamin D sufficient female patients. But CRP, fibrinogen, blood glucose, HbA1c levels and HOMA-IR were not different in these two groups. The measu-red parameters were comparable between male patients with and without vitamin D deficiency. In whole group, vitamin D correlated negatively with BMI, HOMA-IR, PTH, ALP and positively with creatinine.

In our study, we observed increased prevalence of vitamin D deficiency in patients with type 2 DM, especially in obese female patients wearing covered dress. While there was an association between vitamin D and insulin resistance, there was no effect of vitamin D deficiency on CRP, fibrinogen and glycemic control.

A total of 132 patients (79 women and 53 men) were enrolled the study.

We aimed to investigate the prevalence of 25-hydroxyvitamin D deficiency and the effect of vitamin D deficiency on sensitive C-reactive protein (CRP), fibrinogen, lipid, lipoprotein levels, glycemic control and insulin resistance in patients with type 2 diabetes mellitus (DM).