ÖZ
Nazofarengeal karsinom (NFK), kendine özgü etiyoloji, epidemiyoloji ve biyolojik özelliklerle karakterize, benzersiz bir baş ve boyun skuamöz hücreli karsinom türüdür. Boyunda şişlik en sık görülen başvuru belirtisidir; ancak vücudun diğer bölgelerini içeren jeneralize lenfadenopati nadiren bildirilmiştir. Şiddetli anemi, lökositoz ve trombositopeni de nadir olmakla birlikte ileri evrede ortaya çıkabilir. Bu atipik klinik bulguların bir arada görülmesi, NFK yerine daha sık görülen bir hastalık olan lenfoma tanısının konulmasına yol açabilmektedir. Ayrıca, hematolojik bozukluklar kötü prognoz göstergeleridir. Klinisyenlerin, tedavide gecikmelerin ve genel sağkalımın kötüleşmesinin önlenmesi için bu atipik bulguların farkında olması gerekmektedir.
Anahtar Kelimeler:
Anahtar kelimeler: Nazofarengeal karsinom, jeneralize lenfadenopati, şiddetli anemi, lökositoz, trombositopeni
Kaynaklar
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