ABSTRACT
Malignant hyperthermia (MH) is a rare but fatal anaesthetic emergency. It is an autosomal dominant (AD) inherited disorder which is characterized by a hypermetabolic response of an individual upon exposure to a certain type of anaesthesia. We report a rare case of desflurane-induced MH in a Malay descent immediately following an uneventful exposure to sevoflurane. The administration of dantrolene in the immediate management successfully treated the patient.