ABSTRACT

We found that 6 months vitamin D supplementation had positive effects on depressive symptoms and HRQoL, but it didn’t effect body composition and handgrip strength in vitamin D insufficient healthy adults.

There was statistically significant improvement in both depression scores (19.0 [13-26] vs 8.0 [3-14], p=0.002) and most of HRQoL scoring components (physical functioning (61.0±22.9 vs 69.0±22.0, p=0.02), vitality (30.0 [23-38] vs 55.0 [40-75], p <0.001), bodily pain (52.0 [35-66] vs 74.0 [59-91], p=0.004), physical role functioning (0.0 [0.0-75.0] vs 75.0 [0.0-100], p=0.001), emotional role functioning (0.0 [0-33] vs 67 [0-100.0], p=0.001), social role functioning (37.0 [23-48] vs 50.0 [35-63], p=0.01) and mental health (44.0 [22-56] vs 64.0 [50-78], p=0.002) after vitamin D supplementation. But there were no significant difference in body composition and handgrip strength before and after vitamin D supplementation (p>0.05).

Thirty-one vitamin D insufficient (serum level <30 ng/ml) healthy participants were included in the study. Bioelectrical impedance analysis (BIA), handgrip strength, Short Form Health Survey 36 (SF-36) scores and Beck depression inventory (BDI) scale were compared before and after 6 months 25 (OH) vitamin D supplementation.

Vitamin D deficiency/insufficiency is a high prevalent worldwide health problem in all age groups. Data regarding whether vitamin D insufficiency is assocciated with any effects on body composition, quality of life and depressive symptoms in healthy adults is limited. Our aim was to evaluate the effects of vitamin D supplementation on body composition, depression and health-related quality of life (HRQoL) in vitamin D insufficient healthy adults.