ABSTRACT

The widespread access of the society to mobile phones and their intensive use cause health concerns. This study is aimed to investigate the possible histopathological effects of exposure to Radio-frequency Radiation (RFR) originating from mobile phones rat heart and spleen tissue.

Totally 14 Sprague Dawley male rats were used and divided into 2 group (n= 7 for each); sham-control group, exposure group. RFR exposure group was exposed to 2100 MHz GSM-like RFR for 5 hours/day, for 14 days. Heart and spleen tissues of all rats were sampled for histopathological examination and hematoxylin-eosin staining was performed. For p53 examination, immunohistochemical staining was also used in both tissues.

Histopathological and immunohistochemical evaluation revealed no significant changes in heart tissue, but trabecular irregularity and enlargement of sinusoids were observed in the spleen in histopathological evaluation.

It was observed that short-term RFR exposure did not cause significant morphological changes in heart and spleen tissue. This situation may be seen due to the protective effect of the body against RFR.