ABSTRACT

The performance status, stage, nodal involvement, presence of anemia are the prognostic factors affecting the survival in patients with non-small cell lung cancer

There were 71male and 9 female patients with the median age of 55 years (range, 39 to 71). Forty-six-point-three percent of the patients had squmous cell cancer and 35 % had adenocarcinoma. Thirty-one patients had stage I, 30 had stage II and 19 had stage IIIA disease. Forty-six percent of the patients had adjuvant radiotherapy and 50.7% had adjuvant chemotherapy. The median follow-up time after diagnosis was 34.2 months (range, 12 -132), the 5-year overall survival and the 5-year disease free survival rates were 45.5% and 32.8%, respectively. Performance status (p=0.024), tumor size (p=0.015), lymph node involvement (p=0.015) and anemia (p=0.001) were the prognostic factors associated with the overall survival. Stage (p=0.005), anemia(p=0.007) and adenocarcinoma subtype (p< 0.001) significantly affected the disease free survival

Seven-hundred-thirty-eight non-small cell lung cancer patients diagnosed and followed up between the years of 1999 and 2009 were evaluated retrospectively. Eighty patients who underwent surgery were included in the study

Although early-stage lung cancer patients are curable, the prognosis is limited and the 5-year survival rates range from 40 to 65 percent. In this study, clinicopathologic features, treatment responses and prognostic factors of non-small cell lung cancer patients treated with surgery were investigated