ABSTRACT

A 29-year-old female patient, complaining of squeezing retrosternal chest pain, was admitted to our emergency department. Her angina pectoris had started fifteen days ago and accentuated during the last two days. In her medical history, it was determined that during the last four years she had been admitted to hospitals with the same complaint twice, troponins were found to be elevated, she was hospitalized and coronary angiography (CAG) was totally normal. The young woman with recurrent acute coronary syndrome had a mutation in the MTHFR gene. On the determination of normal coronary arteries, we have demonstrated the localization of myocardial infarction via magnetic resonance imaging. In our case we have found no other risk factors except MTHFR 1298 gene mutation for coronary artery disease. MTHFR 1298 gene mutation may cause this state of hypercoagulopathy.