ISSN: 2147-2092
The Relation between Childhood Obesity and MC4R Gene and Near MC4R Polymorphisms
PDF
Cite
Share
Request
Review
VOLUME: 31 ISSUE: 1
P: 83-85
January 2020

The Relation between Childhood Obesity and MC4R Gene and Near MC4R Polymorphisms

GMJ 2020;31(1):83-85
DOI: 10.12996/gmj.2020.24
Ozgur Erkal 1,2
Mehmet Ali Ergun 1
Mehmet Boyraz 3
Aysun Bideci 3
Peyami Cinaz 3
1. Gazi University Faculty of Medicine Department of Medical Genetics, Ankara, Turkey
2. Ministry of Health Antalya Education and Research Hospital, Department of Genetics, Antalya, Turkey
3. Gazi University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, Turkey
No information available.
No information available
Received Date: 04.12.2018
Accepted Date: 19.11.2019
PDF
Cite
Share
Request

ABSTRACT

Childhood obesity, especially in the developed countries including all over the world has an increasing prevalence. Regarding the major impact on public health perspective, childhood obesity should be monitored closely. Many researchers reported MC4R gene and near MC4R region polymorphisms to predispose monogenic obesity both in children and adults. In this study we investigated the relation between childhood obesity and Ser58Cys, Val50Met, Ile102Ser, Val103Ile, Asn274Ser, rs17782313 and rs17700633 polymorphisms in MC4R gene and near MC4R region in the Turkish population. It is very important to detect single gene disorders that may cause childhood obesity in order to screen children for the predisposition of obesity, as to protect them from environmental factors that may cause weight gain.